At Highmark Stadium, James Cook and the Buffalo Bills face Travis Kelce and the Kansas City Chiefs in a matchup featuring two of the NFL's most offensive stars on Sunday at 4:25 p.m. ET.
Offensively, the Bills were a top-five unit and ranked third-best in the NFL with 29 points per game. They rank ninth in defense (19.3 points allowed per game). The Chiefs rank 10th in the NFL with 346.7 total yards per game, but have been lifted by their defense, which ranks fourth-best with just 289.9 total yards per game.
Bills vs. Chiefs: Live streaming information, TV channel and game time
Bills vs Chiefs betting lines
NFL odds courtesy of BetMGM. Odds updated at 8:22 p.m. ET on Saturday. For a complete list of sports betting odds, see USA TODAY Sports Betting Results Odds Hub.
- Distribution favorite: Bills (-2.5)
- Money line: Bills (-130), Chiefs (+110)
- In total: 46 points
Gannett may earn revenue from sports betting operators for referring viewers to betting services. Sports betting providers have no influence on the newsrooms or reporting and are in no way dependent on these revenues. General terms and conditions apply. The general terms and conditions can be found on the operator's website. If you or someone you know has a gambling problem, help is available. Call the National Council on Problem Gambling 24 hours a day at 1-800-GAMBLER (NJ, OH), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA), 1-800- 9- on. WITH-IT (IN). You must be at least 21 years old to play. Sports betting and gambling are not legal everywhere. Make sure you comply with the laws where you live.
We may occasionally recommend products and services that may be of interest to you. If you make a purchase by clicking one of the links, we may receive an affiliate fee. However, Bills Wire operates independently and this has no influence on our reporting.
